Diagnostics, CDK4/6i & ADC


RXponder; TAILORX
SABCS 2022
Part 1: Encouraging data that supports treatment…


SWOG S1207; monarchE; RIGHT choice
SABCS 2022
Part 2: Treamtent options in high-risk breast cancer


TROPiCS-02
SABCS 2022
Part 3: Testing for TROP-2 not needed / no prognostic…
DESTINY-Breast02 & Breast03


DESTINY-Breast 02; DESTINY-Breast 03
SABCS 2022
Practice Changing ADC data confirmed
New Treatment Perspectives


CAPitello-291; PACE
SABCS 2022
New treatment perspectives in luminal breast cancer


EMERALD; SERENA-2
SABCS 2022
SERDs - who benefits? ESR1 testing required?


STIC CTC
SABCS 2022
New insights: Are CTCs predictive or not?
CDK4/6i, ADC, Pregnancy


POSITIVE
SABCS 2022
New evidence regarding the chance of pregnancies in EBC


TROPiCS-02
SABCS 2022
ADC: Do we need a target? Do we need a predicitve…


monarchE
SABCS 2022
monarchE confirms increasing benefit. What are the real…


RIGHT Choice
SABCS 2022
RIGHT choice against Chemotherapy for aggressive…
EBC Highlights


monarchE
SABCS 2022
Abemaciclib as standard of in high-risk HR+ HER2-…


APT
SABCS 2022
Adjuvant TH confirms excellent logn-term follow-up


TailorX
SABCS 2022
Chemo without benefit in node-negative disease


monarchE
SABCS 2022
Time to reconsider Ki-67 threshold?!


POSITIVE
SABCS 2022
First trial about pregnancy in premenopausal early BC…


SABCS 2022
Platin-based neoadjuvant therapy in early TNBC: impact…


IDEAL
SABCS 2022
Benefit of extended adjuvant treatment with endocrine…


POSITIVE
SABCS 2022
Interruption of endocrine therapy in case of desire to…


TRIO-US B-12 TALENT
SABCS 2022
T-DXd as (neo)adjuvant treatment HR+/HER2- patients


monarchE
SABCS 2022
monarchE confirms data once more.


POSITIVE
SABCS 2022
POSITIVE-Trial shwos that temporal therapy interruption…


POSITIVE
SABCS 2022
Good news for young patients
EBC highlights - Multilanguage


SABCS 2022
T-DXd as (neo)adjuvant treatment HR+/HER2- patients


IDEAL
SABCS 2022
Beneficio del tratamiento hormonal extendido según…


POSITIVE
SABCS 2022
El primer estudio sobre la gestación en pacientes con…


POSITIVE
SABCS 2022
POSITIVE-Trial dimostra che l'interruzione temporanea…


SABCS 2022
Neoadyuvancia con carboplatino en cáncer de mama precoz…
MBC highlights


RIGHT choice
SABCS 2022
Targeted approach for endocrine responsive visceral…


EMERALD; SERENA-2
SABCS 2022
Highlights on oral SERDS in HR+ mBC


SERENA-2
SABCS 2022
SERENA-2 showed better PFS by camizestrant compared…


RIGHT Choice
SABCS 2022
A shift from chemotherapy to CDK4/6


ROSET-BM
SABCS 2022
Progress in research and clinic
MBC Highlights - Multilanguage


EMERALD; SERENA-2
SABCS 2022
Highlights on oral SERDS in HR+ mBC


RIGHT choice
SABCS 2022
Il miglior approccio per la malattia…


SERENA-2
SABCS 2022
SERENA-2 ha mostrato una migliore PFS grazie a…
MBC highlights CDK4/6i


DETECT V
SABCS 2022
De-escalation in triple positive MammaCa


RIGHT Choice
SABCS 2022
RIB + ET appears to be the better option than…


RIGHT Choice
SABCS 2022
HR+/HER2-: Who still needs chemotherapy?


RightChoice
SABCS 2022
Ribociclib + endocrine in high risk HR+/HER2- MBC…


RIGHT Choice
SABCS 2022
CDK4/6 inhibitors - a preferred option also for the…


RIGHT Choice
SABCS 2022
Endocrine combination despite visceral crisis


PACE
SABCS 2022
Continuing Palbociclib beyond progression does not…


RIGHT Choice
SABCS 2022
Treatment alternatives to chemotherapy for visceral…
MBC highlights CDK4/6i - Multilanguage


RIGHT Choice
SABCS 2022
Inhibitory CDK4/6 opcją z wyboru również u chorych…
MBC highlights ADC


DESTINY-Breast03
SABCS 2022
T-Dxd - ready for prime time in the 2nd line


DESTINY-Breast03
SABCS 2022
T-DXd new standard after pretreatment with trastuzumab…


TRIO-US B-12 TALENT
SABCS 2022
Chemotherapy-free (neo)adjuvant treatment seems…


DESTINY-Breast02, DESTINY-Breast03
SABCS 2022
Optimal side effect management required


DESTINY-Breast03
SABCS 2022
Important OS update for T-DXd


EMERALD; SERENA-2; CAPItello-921; DESTINY-Breast 02; DESTINY-Breast 03
SABCS 2022
Positive data for ER+ and HER2+ breast cancer


DESTINY-Breast02
SABCS 2022
T-DXd as therapy of choice even after T-DM1 in HER2+…


DESTINY-Breast02; DESTINY-Breast03
SABCS 2022
T-DXd with so far unkown efficacy


DESTINY-Breast02; DESTINY-Breast03
SABCS 2022
T-Dxd keeps us excited


DESTINY-Breast02
SABCS 2022
Great data - as usual with T-Dxd


DESTINY-Breast02; DESTINY-Breast03
SABCS 2022
Robust benefit of T-Dxd confirmed with new data


DESTINY-Breast03
SABCS 2022
Clinically relevant and statistically significant…


DESTINY-Breast02
SABCS 2022
TDXd is the prefered option for pts previously treated…
MBC highlights ADC - Multilanguage


DESTINY-Breast02; DESTINY-Breast03
SABCS 2022
T-DXd – skuteczność, jakiej dotąd nie znaliśmy


DESTINY-Breast03
SABCS 2022
Beneficio clínicamente y estadísticamente significativo…


DESTINY-Breast02
SABCS 2022
TDXd es la primera opción para pacientes tratados…


SABCS 2022
Positive data for ER+ and HER2+ breast cancer


DESTINY-Breast03
SABCS 2022
Importante actualisation des données de survie globale…
MBC highlights SERD


EMERALD; SERENA-2; PACE
SABCS 2022
Oral SERDs are superior


EMERALD; SERENA-2; CAPItello-921; DESTINY-Breast 02; DESTINY-Breast 03
SABCS 2022
Positive data for ER+ and HER2+ breast cancer


EMERALD; SERENA-2
SABCS 2022
A new drug in the endocrine landscape


EMERALD; SERENA-2
SABCS 2022
oral SERDs on the rise?
MBC highlights SERD - Multilanguage


EMERALD; SERENA-2
SABCS 2022
Una nouva molecola nel trattamento ormonale del tumore…


SABCS 2022
Positive data for ER+ and HER2+ breast cancer


EMERALD; SERENA-2
SABCS 2022
Une nouvelle molécule dans le traitement hormonal du…
MBC highlights Varia


POSITIVE
SABCS 2022
Pregnancies after primary breast cancer


EMERALD; SERENA-2; DESTINY-Breast 02; DESTINY-Breast 03
SABCS 2022
ADC or other therapies after CDK4/6


EMERALD; SERENA-2; CAPItello-921; DESTINY-Breast 02; DESTINY-Breast 03
SABCS 2022
Positive data for ER+ and HER2+ breast cancer


GeparOLA
SABCS 2022
Olaparib as an alternative to carboplatin in aggressive…


CAPitello-291
SABCS 2022
AKT inhibitor capivasertib in HR+ mBC


SABCS 2022
Estradiol withdrawal affects the micromillieu in the…


STIC CTC
SABCS 2022
CTC count may help in therapy decisions


CAPitello-291
SABCS 2022
Promising new player in the second line setting in…


SABCS 2022
Her2-low discordance rate at 40%


DETECT V
SABCS 2022
Triple-positive MBC does not require chemotherapy.


CAPitello-291
SABCS 2022
Capivasertib - A drug for allcomers


STIC CTC
SABCS 2022
CTCs with metastatic breast cancer re-visited
MBC highlights Varia - Multilanguage


SABCS 2022
Positive data for ER+ and HER2+ breast cancer


STIC CTC
SABCS 2022
Le compte des CTC peut orienter la décision…


CAPitello-291
SABCS 2022
Obiecująca nowa opcja w drugiej linii zaawansowanego,…


CAPitello-291
SABCS 2022
Capivasertib un nuovo standard per tutti?
eBC Year in Review


TailorX; ADAPT; monarchE; iSPY; POSITIVE; OlympiA
Year in Review 2022
HR+ - Practice changing data - which therapy for which…


KEYNOTE-522; NACT Gupta et al.; OlympiA
Year in Review 2022
TNBC - Practice changing data lead to new approvals -…


APHINITY; KAITLIN; perELISA; ADAPT; IMpassion050
Year in Review 2022
HER2+ - no new approval but long-term follow up data…
mBC Year in Review


RIGHT Choice; MONARCH 3; PALOMA-2; EMERALD; AMEERA; acelERA BC
SABCS 2022
The Right Choices? CDK4/6i vs. Chemo, SERDs & ESR1?


DESTINY-Breast02; DESTINY-Breast03; DETECT V; HER2CLIMB; TUXEDO-1; KEYNOTE-355
SABCS 2022
Dealing with Brain mets / Update TNBC


DESTINY-Breast02; DESTINY-Breast03; TROPICS-02; DESTINY-Breast04
SABCS 2022
New Indications: ADCs & HER2-low