ASCO 2023

Sonia trial: How does the new data change clinical practice - or does it at all? Insights from Italy, United States and Germany.

Discussions and controversies on social-media: what is the impact of science-twitter discussions on the everyday practice in oncology?

ADC revolution: How can the new results be integrated in clinical practice? Which studies are in sight and which ones do we need in the future?

CDK4/6i in EBC: Have abema and ribo arrived in the early setting? Insights from North America and Europe

CDK4/6 inhibitors in EBC: Amazing data, but longer follow up needed!

Expanding CDK4/6i therapy in EBC: How to select patients for the right therapy?

PART2: Trying to understand optimal therapy for pre-menopausal women - promising results, but still long way to go!

PART1: How to de-escalate chemotherapy? What is the best strategy to identify patients who don´t need chemotherapy?

Chemotherapy de-escalation in HER2+ patients: Consequences of the PHERGain data on daily practice?!

New data on Ribocilib in adjuvant setting EBC: What does it change immediately, what changes are expected in the future? Perspectives from Europe and Northern America

Data from Meta-Analyses of almost 15k Patients: Who benefits from ovarian function suppression?

Early follow-up shows clear benefit

Response adapted, chemotherapy-free option in HER2+ EBC

10 years update on ShortHER

TILs subtypes are associated with clinical features and prognosis in HR+/HER2- BC

Ribociclib has arrived in the adjuvant setting

Palbociclib after Palbociclib might not be the best option

Can we preserve our patients form chemotherapy?

SOC of ovarian ablation confirmed in meta-analysis.

Discussions on CDK4/6 inhibitors in EBC

White blood cells with increasing prognostic relevance? Data from the GeparNuevo Study

Tumor-informed ctDNA likely prognostic for relapse in ER positive and HER2 negative EBC

PHERGain opens the possibility to avoid chemotherapy in HER2+ breast cancer

More CDK4/6 options for EBC patients

A challenge for clinical management

My EBC highlights from ASCO23

TILs in HER2+ disease - prognostic, but not enough to deescalate

Ribociclib improves iDFS

De-escalation of CT for early BC

Another proof of efficacy of immunotherapy in advanced TNBC

Young patients benefit from ovarian suppression

Practice changing or not quite yet?

Ovarian function - Ovarian suppression not necessary in young patients?

First data with adjuvant ribociclib

From PENELOPE-B to SURVIVE

TILs are prognostic but not predictive in HER2+ EBC

Analyses of ctDNA in PENELOPE-B: Test methods are increasingly accurate

1/3 of patients with HER2+ in future without chemotherapy?

Checkpoint inhibition in endometrial cancer: new therapy algorithms needed

Chemo-immunotherapeutic signals especially in HER2low possibly predictive of chemotherapy response in EBC

TILs Subtypen sind assoziiert mit klinischen Merkmalen und Prognose beim HR+/HER2- BC

TILs sind prognostisch aber nicht prädiktiv beim HER2+ eBC

Palbociclib después de Palbociclib podría no ser la mejor opción

I miei punti salienti di ASCO23

Czy wystarczy, aby zmienić standardy?

Response adaptierte, Chemotherapie-freie Option beim HER2+ eBC

Eine Herausforderung für das klinische Management

Kolejny dowód na skuteczność immunoterapii w zaawansowanym raku trójujemnym

PHERGain abre la posibilidad de evitar la quimioterapia en el cáncer de mama HER2+

Chemo-IO Signale bei HER2low prädiktiv für Ansprechen der Chemotherapie

Tumor-informed ctDNA wahrscheinlich prognostisch für einen Rückfall beim ER positive und HER2 negative eBC

TILs w rakach HER2+ - znaczenie rokownicze, ale nie droga do deeskalacji leczenia

Ovar Funktion - Ovarielle Supression verzichtbar bei jungen Patientinnen?

1/3 der Patientinnen mit HER2+ zukünftig ohne Chemotherapie?

Von PENELOPE-B zur SURVIVE

Eine Herausforderung für viele Patienten, wenig Doktoren

Primele date cu ribociclib adjuvant

NATALEE nicht überraschend aber überzeugend positiv

SOC der ovarialen Ablation in der Metaanalyse bestätigt

What is the optimal therapie sequence for HR+ MBC patients?

Molecular imaging for endocrine responsivness

E-Health Applications in Oral Cancer Therapy

Updates on ADCs in metastatic breast cancer

CDK4/6 i beyond CDK4/6 i: one more piece to the puzzle

The start of precision medicine in HR+ breast cancer

Continued OS benefit for Sacituzumab Govitecan

Mises à jour sur les ADC dans le cancer du sein métastatique

Aggiornamenti sugli ADC nel carcinoma mammario metastatico

CDK4/6i dopo CDK4/6i, un altro pezzo del puzzle: lo studio PALMIRA

Update ADC efficacy

CDK4/6i in first line and beyond & Biomarkers

The value of eHealth

CDK4/6 Sequencing? ESR-1 not ready for prime time? Palbo rechallenge?

PAPR-inhibitors: Patient-selection matters!

Part 1: Important update on testosterone-recovery

Part2: Important update on testosterone-recovery

Confirming results for PARPi in mCRPC

LuPARP combination study: LuPSMA and Olaparib in mCRPC

Metastasis-directed for prostate cancer

AI for prediction in local prostate carcinoma

ARASEC: ADT + Daralutamide for mHSPC

PSA nadir 6 month after Radiotherapy is strong prognostic marker for survival

TALAPRO-2: Results and controversies

Reassuring real-world data!

PRL-02: Intramuscular arbiraterone

Intensified or de-intensified therapy in mHSPC

Over-staging of bone scan compared with PSMA PET/CT

DEAR trial: real-world comparator analyses of ARIs

PEACE 1 - results and controversies

LuPARP studien: 177-Lu-PSMA och olaparib vid mCRPC

PSA nadir 6 månader efter radioterapi är en prognostisk markör för överlevnad

Skelettscintigrafi ospecifikt jämfört med PSMA PET-CT

PARP-inhibitors: La selección de pacientes es importante

Intensifierad eller de-intensifierad behandling vid mHSPC?

Επιβεβαίωση αποτελεσμάτων για το PARPi στο mCRPC

Triple therapy in mCSPC - which is the ideal partner for radiotherapy? And which patients should received irradiation?

PARPi in PCa: more genetic testing is required as PRO data demand better patient selection

What is your preferred sequence in 1st line treatment and how you treat after progress?

Q-TWiST in the therapy of aUC

Best of Bladder: ddMVC increases DFS! Standard dissection SOC? FGFR targeting showing efficacy!

The beginning of a new era in urothelial cancer?!

New standard for MIBC

First line in cisplatin-ineligible advance urothelial cancer: It´s getting busy out there

New SoC option for metastatic bladder cancer

FGFR inhibition

Extent of lymphadenectomy in cystectomy

Targeted therapies in advanced urothelial cancer: The renaissance?!

Enfortumab vedotin + pembrolizumab 1stL in cisplatin-ineligible patients

Nouvelles options de soins standard pour le cancer de la vessie métastatique

Terapias dirigidas al cáncer urotelial avanzado: ¡¿El renacimiento?!

Primera línea en cáncer urotelial avanzado no elegible para cisplatina: Hay mucho trabajo ahí fuera

Best of Bladder: ddMVC increases DFS! Standard dissection SOC? FGFR targeting showing efficacy!

The efficacy of neo-adjuvant therapy (ddMVAC, Cisplatinum)

The efficacy of FGFR targeting

Update EV/Pembro, Avelumab Maintenance

Non ccRCC: how should we treat patients today?

The impact of microbiome and supplements on therapy efficacy

Long term follow up in advanced renal cell cancer: Is everything clear, yet?

Primary endpoint not reached: what do we learn from CONTACT-03 results?

News from the adjuvant

Long-term follow-up for IO/TKI in mRCC

Update and take home message of 1st Line mRCC

New data non ccRCC

New standard for 2nd line RCC?

IO rechallenge in mRCC

Lenvatinib + pembrolizumab in non-clear cell renal cell carcinoma

1st Line therapy RCC: which combination to choose?

ADAURA: Osimertinib improves survival in the treatment of EGFRm rNSCLC

The value of perioperative chemo-IO in rNSCLC and the importance of staging

Perioperative treatment

A new standard of care

A new standard of care for operated patients with eGFRmut adenocarcinoma

More options in the perioperative setting

CheckMate 9LA: 4‑year clinical update

EGFR testing necessary in the adjuvant setting

OS benefit from EGFR receptor TKI

An imperfect analysis, but perfect results

A chemo-free preop. IO strategy?

ADAURA - Discussion closed?

Induction options in the perioperative setting

Another neoadjuvant chemo/IO option

Adjuvant and neoadjuvant strategies in resectable NSCLC

Confirmation of neoadjuvant immunotherapy

ADAURA - results and controversies

Which should we prefer: neoadjuvant, adjuvant or perioperative chemo/IO?

Adjuvant IO in KRASm patients

Role of periopertative IO confirmed

Added benefit of perioperative chemo/IO in stage 2-3b NSCLC

Toegevoegde waarde van periperatief chemo-immuno bij stadium II-IIIB NSCLC

Un nouveau standard therapeutique pour les patients opérés d’un adenocarcinome EGFR muté

Que devrions-nous préférer: traitement néoadjuvant, adjuvant ou chimio/IO périopératoire?

Más opciones en el entorno perioperatorio

Stratégies adjuvantes et néoadjuvantes dans le CBNPC résécable

Rolle der periopertativen IO bestätigt

ADAURA- discussie gesloten?

Update on KRASG12Cm treatment options - how to proceed?

TTF-treatment requires further studies

Zorifertinib: an option when osimertinib is not available

Sotorasib: clear clinical benefit, but short follow-up time

Does ADC + chemo + IO replace the existing concepts?

Pembro + chemo in pts with TKI-resistant EGFRm / Sunvozertinib - a drug for Exon20 insertions

CORRELATE - a real world analysis

IO in EGRF positive patients post TKI

TROP2-ADC shows high response rates in 1L-combination therapy, but safety must be observed

Stopping treatment is ok

ADC + ICI ± Pt-CT in patients with aNSCLC

LUNAR: TTF medical device shows OS-benefit, but more information needed

Hyperfractionation - an interestingh concept, but not for every patient

New data from another BiTE

More BiTEs, more possibilities

Treatment strategies in SCLC

A positive trial with no impact

Hyperfractionated radiotherapy for SCLC

Can we incoporate biomarkers in SCLC treatment?

Kunnen we biomarkers gebruiken om behandeling te selecteren voor SCLC?

Stratégies de traitement dans le SCLC

Más BiTEs, más posibilidades

Immune checkpoint inhibitors in malignant mesothelioma

ONCOalert (inclusive patient advocates) consensus on the results of the PROspect trial

No practice-changing data in mesothelioma, other studies to await

Immun-Checkpoint-Inhibitoren beim malignen Mesotheliom